A Awada Selected Research

MSC1992371A

2/2014

A phase I schedule dependency study of the aurora kinase inhibitor MSC1992371A in combination with gemcitabine in patients with solid tumors.

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A Awada Research Topics

Disease

27	Neoplasms (Cancer) 01/2023 - 01/2000
24	Breast Neoplasms (Breast Cancer) 01/2023 - 02/2000
7	Melanoma (Melanoma, Malignant) 06/2015 - 01/2000
5	Neoplasm Metastasis (Metastasis) 01/2023 - 02/2010
4	Brain Neoplasms (Brain Tumor) 01/2023 - 05/2011
4	Squamous Cell Carcinoma of Head and Neck 09/2017 - 04/2004
4	Head and Neck Neoplasms (Head and Neck Cancer) 02/2016 - 01/2000
3	Fatigue 10/2015 - 02/2001
3	Ovarian Neoplasms (Ovarian Cancer) 03/2004 - 11/2003
2	Triple Negative Breast Neoplasms 01/2019 - 04/2014
2	Neutropenia 04/2014 - 02/2001
2	Lymphatic Metastasis 04/2013 - 11/2011
2	Stomatitis 12/2008 - 04/2002
2	Exanthema (Rash) 03/2006 - 03/2003
2	Carcinogenesis 05/2004 - 09/2003
2	Vomiting 11/2003 - 02/2001
2	Pain (Aches) 03/2003 - 12/2002
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2023
1	Autoimmune Diseases (Autoimmune Disease) 01/2023
1	Infections 01/2023
1	Hypersensitivity (Allergy) 09/2017
1	Adrenal Insufficiency (Adrenal Gland Hypofunction) 07/2016
1	Prostatic Neoplasms (Prostate Cancer) 07/2016
1	Pancreatic Neoplasms (Pancreatic Cancer) 10/2015
1	Dysgeusia (Parageusia) 08/2013
1	Renal Cell Carcinoma (Grawitz Tumor) 09/2012
1	Colorectal Neoplasms (Colorectal Cancer) 07/2012
1	Inflammatory Breast Neoplasms 05/2011
1	Disease Progression 02/2010

Drug/Important Bio-Agent (IBA)

7	Docetaxel (Taxotere)FDA Link 09/2017 - 04/2004
6	AnthracyclinesIBA 05/2011 - 04/2002
5	Gemcitabine FDA Link 10/2015 - 04/2002
4	Cisplatin (Platino)FDA LinkGeneric 09/2017 - 11/2003
4	Fluorouracil (Carac)FDA LinkGeneric 09/2017 - 03/2002
4	Messenger RNA (mRNA)IBA 09/2017 - 11/2011
4	Proteins (Proteins, Gene)FDA Link 06/2015 - 10/2000
4	Trastuzumab (Herceptin)FDA Link 05/2011 - 09/2003
3	DNA (Deoxyribonucleic Acid)IBA 09/2017 - 11/2011
3	Monophenol Monooxygenase (Tyrosinase)IBA 06/2015 - 11/2011
3	Paclitaxel (Taxol)FDA LinkGeneric 04/2014 - 02/2000
3	Taxoids (Taxanes)IBA 03/2013 - 04/2002
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2023 - 09/2017
2	SteroidsIBA 01/2023 - 07/2016
2	Estrogen ReceptorsIBA 01/2023 - 10/2003
2	Tyrosine Kinase InhibitorsIBA 01/2022 - 01/2013
2	neratinibIBA 01/2019 - 01/2013
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2017 - 09/2003
2	cabazitaxel FDA Link 07/2016 - 05/2011
2	Transaminases (Aminotransferases)IBA 10/2015 - 04/2002
2	Lapatinib (GW572016)FDA Link 12/2013 - 05/2011
2	Temozolomide (Temodar)FDA LinkGeneric 12/2013 - 06/2004
2	Sorafenib (BAY 43-9006)FDA Link 09/2012 - 03/2006
2	AcidsIBA 12/2004 - 12/2001
2	liposomal doxorubicin (Doxil)FDA Link 06/2004 - 06/2002
2	CreatinineIBA 11/2003 - 02/2001
2	Methotrexate (Mexate)FDA LinkGeneric 03/2003 - 03/2002
2	Doxorubicin (Adriamycin)FDA LinkGeneric 06/2002 - 02/2000
1	B7-H1 AntigenIBA 01/2023
1	Programmed Cell Death 1 ReceptorIBA 01/2023
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2023
1	Phenobarbital (Luminal)FDA Link 01/2023
1	Immune Checkpoint InhibitorsIBA 01/2023
1	pembrolizumabIBA 01/2019
1	Cetuximab (Erbitux)FDA Link 09/2017
1	abirateroneIBA 07/2016
1	Adrenal Cortex Hormones (Corticosteroids)IBA 07/2016
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 04/2016
1	zirconium-89-trastuzumabIBA 04/2016
1	Ado-Trastuzumab EmtansineIBA 04/2016
1	Circulating Tumor DNAIBA 10/2014
1	LipidsIBA 04/2014
1	Aurora KinasesIBA 02/2014
1	MSC1992371AIBA 02/2014
1	CP 4126IBA 08/2013
1	Calcium-Binding ProteinsIBA 04/2013
1	Vinorelbine (Navelbine)FDA LinkGeneric 01/2013
1	temsirolimus FDA Link 09/2012
1	Sunitinib (Sutent)FDA Link 09/2012
1	Everolimus FDA Link 09/2012
1	InterferonsIBA 09/2012
1	Bevacizumab (Avastin)FDA Link 09/2012
1	pazopanib FDA Link 09/2012
1	Deoxyglucose (2 Deoxy D glucose)IBA 07/2012
1	FluorineIBA 07/2012
1	tyrosine receptor (receptor, tyrosine)IBA 05/2011
1	taxaneIBA 05/2011
1	XRP6258IBA 05/2011
1	Capecitabine (Xeloda)FDA Link 05/2011
1	Protein Kinases (Protein Kinase)IBA 05/2011
1	Immunoglobulin G (IgG)IBA 02/2010
1	adecatumumabIBA 02/2010
1	Epithelial Cell Adhesion MoleculeIBA 02/2010

Therapy/Procedure

18	Therapeutics 01/2023 - 02/2000
12	Drug Therapy (Chemotherapy) 07/2012 - 01/2000
2	Radiotherapy 12/2008 - 01/2001
1	Duration of Therapy 01/2023
1	Lymph Node Excision (Lymph Node Dissection) 01/2018
1	Hysterectomy 01/2018
1	Castration 07/2016
1	Immunotherapy 02/2016